• Recall the most common symptoms which H2S patients present with 
• Identify which H2S treatment interventions led to a statistically significant rate of adequate patient response 
• Evaluate an H2S SIBO case with a focus on severity and treatment history 
• Determine reasonable treatment options for an H2S SIBO case

Hour 1

• Distinguish what gases are measured with Aire versus Aire2
• Judge the diagnostic agreement between Quintron and Aire devices in patients suspected of having SIBO
• Map the relationship between ‘fermentation scores’ and ppm
• Illustrate how you could use the Aire device to conduct formal SIBO breath tests

Hour 2

• Extrapolate hydrogen levels in the background of high methane
• Compare and contrast the pros and cons of using the Aire device
• Implement the clinician dashboard for breath testing
• Clarify why CO2 levels are not needed for Aire

• Recall the pathophysiology of the progression of Barrett’s esophagus to adenocarcinoma
• Implement the 2022 ACG guidelines on the use of PPIs for Barrett’s esophagus
• Evaluate the conclusions from the three competing meta-analyses on PPIs for Barrett’s
• Apply relative risk reduction calculations to the determination of the benefit of PPIs for Barrett’s

• Describe the role of GRADE in Guideline development
• Recall the recommendations of the ACG SIBO Guidelines
• Identify key concepts of SIBO as delineated by the authors
• Appraise the ACG Guidelines

• Implement the 2020 ACG Guidelines as it relates to breath testing for patients with IBS.
• Implement the 2020 ACG Guidelines as it relates to breath testing for patients taking PPIs.
• Discriminate between normal and abnormal ppm of H2S on a breath test.
• Contrast between the microbial diversity of the small intestine in those with and without SIBO.
• Identify the aberrant organism most associated with SIBO in the REIMAGINE study.
• Implement the 2020 ACG Guidelines as it relates to testing IBS patients for food sensitivities.
• Implement the 2020 ACG Guidelines as it relates to the use of low FODMAP diets in IBS patients.
• Select the Gut Directed Hypnotherapy regimen associated with the largest effect size.
• Explain the need for GRADE within the context of Guideline development.
• Critique a guideline using the AGREE-II criteria.
• Define the concepts of pre- and post-test probability.
• Calculate a post-test probability.

• Define Small Intestinal Bacterial Overgrowth (SIBO) 
• List common causes/ associations/risk factors of SIBO
• Recall the various estimates of SIBO prevalence
• Explain why SIBO prevalence estimates vary
• Describe the trajectory of SIBO research over the past decades

• Explain the limitations of using breath tests for the diagnosis of SIBO compared to other alternatives.
• Describe the specific issues with glucose-based breath tests for SIBO diagnosis.
• Describe the specific issues with lactulose-based breath tests for SIBO diagnosis.
• Critique the North American consensus document on breath testing for SIBO

• Define leaky gut
• Recall basic histology/molecular biology involved in leaky gut
• List conditions associated with leaky gut
• Compare diagnostic tools in the differential diagnosis of leaky gut
• Recite how the lactulose mannitol test works
• List therapeutic interventions for leaky gut

• Summarize the current state of legal status and research on fecal microbial transplants (FMT)
• Describe the state of research of FMT for irritable bowel syndrome
• Describe the state of research of FMT for hepatic encephalopathy
• Describe the state of research of FMT for antibiotic associated diarrhea/dysbiosis
• Describe the state of research of FMT for ulcerative colitis
• Describe the state of research of FMT for Clostridium difficile infection
• Describe the state of research of FMT for autism