• Discuss the prevalence of osteopenia and osteoporosis.
• Describe the relationship between osteoporosis and fragility fracture.
• Contrast the relationship between fragility fracture, morbidity and mortality.
• Differentiate the differences between cortical and trabecular bone.
• Recognize the osteoporosis “care gap” and its driving factors.

• Summarize the bone remodeling cycle.
• Discuss the changes in the bone remodeling cycle with age.
• Discuss the role of declining estrogen in the age-related changes in bone remodeling.
• Discuss the areas of the bone remodeling cycle that allow therapeutic interventions.

Hour 5

• Examine the role of immunosenescence in background systemic inflammation.
• Discuss the role mesenchymal stem cell senescence in osteoporosis.
• Demonsrate senolytic therapy in eliminating senescent cells in osteoporosis.
• Contrast inflammatory resolution with inflammatory suppression.
• Discuss the role of micronutrients in the prevention and treatment of osteoporosis..

Hour 6

• Discuss the role of vitamins D & K2 and minerals the prevention and treatment of osteoporosis.
• Explain the effectiveness of osteo-inductive nutraceuticals in the treatment of osteoporosis.
• Examine the research on the use of hydrolyzed collagen peptides in bone density and strength.
• Discuss the use of bovine bone morphogenic proteins in osteoporosis.
• Contrast the ability of nutrients, therapeutic modalities and medications in the ability of normalize bone remodeling.

Hour 7

• Examine the role of exercise in the prevention and treatment of osteoporosis.
• Discuss the evidence supporting the efficacy of laser therapy in osteoporosis including in vitro cell studies, animal models and human studies both for fracture and osteoporosis.
• User laser therapy to normalize the bone remodeling cycle in osteoporosis.
• Discuss the cell receptor and signaling pathways in osteoblasts and osteoclasts that are receptive to pulsed electromagnetic frequency (PEMF) therapy interventions.
• Apply the “cross-talk” effect of PEMF therapy on bone.

 Hour 8

• Discuss the evidence supporting the efficacy of pulsed electromagnetic frequency therapy in osteoporosis including in vitro cell studies, animal models and human studies both for fracture and osteoporosis.
• Examine the positive “spillover effect” of laser therapy and PEMF therapy of osteoarthritis in the treatment of osteoporosis.
• Summarize the clinical trials of PEMF therapy for osteoporosis.
• Discuss the importance of pulse frequency in the application of PEMF therapy.
• Examine the comorbidity between osteoporosis and osteoarthritis.

Hour 9

• Examine the osteoporosis risk in patients with chronic respiratory diseases.
• Discuss the unique treatment considerations corticosteroid induced osteoporosis.
• CortioSterioid -  Same comments as above about drug therapy
• Discuss the treatment of osteoporosis induced but pulmonary disease and its associated therapies.
• CortioSterioid -  Same comments as above about drug therapy 
• Summarize the factors associated with the high prevalence of osteoporosis in rheumatic diseases.
• Explore the mechanisms of osteoporosis in type two diabetes independent of bone mineral density.

 Hour 10

• Summarize the dietary patterns associated with bone matrix glycation.
• Discuss the nutraceuticals that inhibit glycation related bone matrix.
• Review case studies of the management of osteoporosis looking at prognostic factors including baseline T scores and co-morbidities.
• Examine specific osteoporosis cases and their approach to management.
• Summarize building an effective non-drug treatment program for osteoporosis.